Spontaneous regression of conjunctival keratoacanthoma

Ghada J. Albayyat, Nandini Venkateswaran, Dan Arreaza, Sander R. Dubovy, Anat Galor, Carol L. Karp

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


An 83-year-old white man presented with a rapidly growing conjunctival mass in his left eye over the course of 1 month. While awaiting surgical intervention, the tumour underwent partial, spontaneous regression to half its original size. The lesion was ultimately excised with wide margins using a no-touch technique and application of cryotherapy to the corneal and conjunctival margins and scleral bed. Histopathological analysis revealed a conjunctival keratoacanthoma. To our knowledge, this is the first case documenting the partial, spontaneous regression of a conjunctival keratoacanthoma over a 5 week time course from the time of diagnosis to surgical excision.

Original languageEnglish (US)
Article numbere228833
JournalBMJ case reports
Issue number7
StatePublished - Jul 1 2019


  • anterior chamber
  • oncology
  • ophthalmology
  • pathology

ASJC Scopus subject areas

  • Medicine(all)


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