Neovascular Glaucoma Following Central Retinal Vein Obstruction

Larry E. Magargal, Gary C. Brown, James J. Augsburger, Richard K. Parrish

Research output: Contribution to journalArticlepeer-review

92 Scopus citations


The results of a prospective clinical and fluorescein angiographic study of 155 patients with central retinal vein obstruction (CRVO) were analyzed to identify risk factors contributing to the subsequent development of iris neovascularization (NVI) and neovascular glaucoma (NVG). Of 144 untreated eyes, 20% developed NVG. The eyes were classified as having either an ischemic or a hyperpermeable type of CRVO according to the extent of retinal capillary nonperfusion demonstrated by the initial fluorescein angiogram. The risk of developing NVG was found to be approximately 60% in those eyes with extensive retinal ischemia. None of the 22 eyes with an ischemic CRVO treated with panretinal photocoagulation (PRP) prior to the onset of NVI developed NVG.

Original languageEnglish (US)
Pages (from-to)1095-1101
Number of pages7
Issue number11
StatePublished - 1981
Externally publishedYes


  • central retinal vein obstruction
  • fundus-iris angiography
  • iris neovascularization
  • neovascular glaucoma
  • panretinal photocoagulation
  • retinal ischemia

ASJC Scopus subject areas

  • Ophthalmology


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