Medication-taking self-efficacy and medication adherence among hiv-infected cocaine users

Drenna Waldrop-Valverde, Chuanhui Dong, Raymond L. Ownby

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


This prospective, observational study tested the ability of self-efficacy for taking antiretroviral medications to predict medication adherence among current and former cocaine and heroin users. Electronic monitors to record bottle openings and self-report measures of medication adherence were used. The sample included 99 men and women who were interviewed at 4-week intervals for 6 months. Mixed effects regression models to test the relationship of substance use and self-efficacy for medication-taking with percent of self-report adherence, dose adherence, number of days adherent, and adherence to medication schedule at each study visit showed that medication-taking self-efficacy was significantly related to all measures of adherence except schedule adherence. Findings also showed that electronically monitored adherence measures declined over the study period whereas self-report adherence did not. Findings suggest that self-efficacy can have a sustained effect on adherence to doses but may not be an influential predictor of adherence to their correct timing.

Original languageEnglish (US)
Pages (from-to)198-206
Number of pages9
JournalJournal of the Association of Nurses in AIDS Care
Issue number3
StatePublished - May 2013


  • Adherence
  • Antiretroviral medication
  • HIV
  • Self-efficacy
  • Substance use

ASJC Scopus subject areas

  • Advanced and Specialized Nursing


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