Lack of association of VEGF promoter polymorphisms with sporadic ALS

W. Chen; M. Saeed; H. Mao; N. Siddique; L. Dellefave; W. Y. Hung; H. X. Deng; R. L. Sufit; S. L. Heller; J. L. Haines; M. Pericak-Vance; T. Siddique

doi:10.1212/01.wnl.0000227926.42370.04

Lack of association of VEGF promoter polymorphisms with sporadic ALS

W. Chen, M. Saeed, H. Mao, N. Siddique, L. Dellefave, W. Y. Hung, H. X. Deng, R. L. Sufit, S. L. Heller, J. L. Haines, M. Pericak-Vance, T. Siddique

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29 Scopus citations

Abstract

The authors tested the association of three vascular endothelial growth factor (VEGF) promoter polymorphisms with sporadic ALS (SALS) to verify the results of a previous study and to investigate their modifier effects on the subphenotypes of SALS in a large family-based and case-control cohort of North American white subjects (N = 1,603). They did not find any association of the VEGF promoter polymorphisms with SALS or its subphenotypes, suggesting that they do not have a direct causal role in ALS.

Original language	English (US)
Pages (from-to)	508-510
Number of pages	3
Journal	Neurology
Volume	67
Issue number	3
DOIs	https://doi.org/10.1212/01.wnl.0000227926.42370.04
State	Published - Aug 2006
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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title = "Lack of association of VEGF promoter polymorphisms with sporadic ALS",

abstract = "The authors tested the association of three vascular endothelial growth factor (VEGF) promoter polymorphisms with sporadic ALS (SALS) to verify the results of a previous study and to investigate their modifier effects on the subphenotypes of SALS in a large family-based and case-control cohort of North American white subjects (N = 1,603). They did not find any association of the VEGF promoter polymorphisms with SALS or its subphenotypes, suggesting that they do not have a direct causal role in ALS.",

author = "W. Chen and M. Saeed and H. Mao and N. Siddique and L. Dellefave and Hung, {W. Y.} and Deng, {H. X.} and Sufit, {R. L.} and Heller, {S. L.} and Haines, {J. L.} and M. Pericak-Vance and T. Siddique",

year = "2006",

month = aug,

doi = "10.1212/01.wnl.0000227926.42370.04",

language = "English (US)",

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TY - JOUR

T1 - Lack of association of VEGF promoter polymorphisms with sporadic ALS

AU - Chen, W.

AU - Saeed, M.

AU - Mao, H.

AU - Siddique, N.

AU - Dellefave, L.

AU - Hung, W. Y.

AU - Deng, H. X.

AU - Sufit, R. L.

AU - Heller, S. L.

AU - Haines, J. L.

AU - Pericak-Vance, M.

AU - Siddique, T.

PY - 2006/8

Y1 - 2006/8

N2 - The authors tested the association of three vascular endothelial growth factor (VEGF) promoter polymorphisms with sporadic ALS (SALS) to verify the results of a previous study and to investigate their modifier effects on the subphenotypes of SALS in a large family-based and case-control cohort of North American white subjects (N = 1,603). They did not find any association of the VEGF promoter polymorphisms with SALS or its subphenotypes, suggesting that they do not have a direct causal role in ALS.

AB - The authors tested the association of three vascular endothelial growth factor (VEGF) promoter polymorphisms with sporadic ALS (SALS) to verify the results of a previous study and to investigate their modifier effects on the subphenotypes of SALS in a large family-based and case-control cohort of North American white subjects (N = 1,603). They did not find any association of the VEGF promoter polymorphisms with SALS or its subphenotypes, suggesting that they do not have a direct causal role in ALS.

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AN - SCOPUS:33747037794

VL - 67

SP - 508

EP - 510

JO - Neurology

JF - Neurology

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ER -

Lack of association of VEGF promoter polymorphisms with sporadic ALS

Abstract

ASJC Scopus subject areas

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