Chronic Pruritus in the Geriatric Population

Taige Cao, Hong Liang Tey, Gil Yosipovitch

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Chronic pruritus (>6 week's duration) in the geriatric population (≥65 years old), is an increasing health care problem. The pathophysiologic predisposing factors are abnormalities of the epidermal barrier, immune system, and nervous system. Causes can be dichotomized into histaminergic and nonhistaminergic pruritus. Topical treatments are generally safe. Systemic treatments are chosen depending on the condition, comorbid diseases, and drug interactions. Treatment options are limited. Progress has been made in identifying itch-selective mediators over the last decade. Numerous new medications are currently undergoing clinical trials and they are anticipated to enter the clinics in the near future.

Original languageEnglish (US)
Pages (from-to)199-211
Number of pages13
JournalDermatologic Clinics
Issue number3
StatePublished - Jul 1 2018


  • Classification
  • Diagnosis
  • Geriatrics
  • Pruritus
  • Therapeutics

ASJC Scopus subject areas

  • Dermatology


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