Amyloidoma: a review and case report

Sohil S. Desai, Michael G. Rizzo, Augustus J. Rush, Andrew E. Rosenberg, Motasem Al Maaieh

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Amyloidoma is a solitary mass of amyloid protein that arises in patients with or without evidence of systemic amyloidosis, and can be found in a variety of different organ systems. Herein, we describe three cases of localized biopsy-positive amyloidomas with no evidence of systemic involvement—primary amyloidoma. Our cases include a patient with a paraspinal soft tissue amyloidoma, a patient with multiple primary amyloidomas involving the thoracic cavity and flank, and a patient with insulin-injection induced amyloidoma of the left shoulder. We present these cases to provide further insights into the clinical presentation of this uncommon clinical entity. We review the pathophysiology of amyloidosis and discuss our cases in the context of previous reports of amyloidoma.

Original languageEnglish (US)
Pages (from-to)437-444
Number of pages8
JournalSkeletal Radiology
Issue number2
StatePublished - Feb 2021


  • Amyloidoma
  • Amyloidosis
  • Drug-induced amyloidoma
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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