Trans-omic analysis of epicardial adipose tissue in atrial fibrillation

Project: Research project

Project Details

Description

Project Narrative Atrial fibrillation is the most common heart rhythm disorder, with a 25% lifetime risk of developing atrial fibrillation once an individual reaches the age of 40 years. Obesity, a very prevalent condition, and epicardial adipose tissue are associated with atrial fibrillation and may be involved in the pathogenesis of the atrial substrate leading to atrial fibrillation; importantly, weight loss improves treatment for atrial fibrillation. This study will assess the proteomic, transcriptomic, and metabolomic features linking epicardial adipose tissue to atrial fibrillation, in order to identify new targets for prevention and treatment.
StatusActive
Effective start/end date2/1/211/31/23

Funding

  • National Heart, Lung, and Blood Institute: $622,495.00
  • National Heart, Lung, and Blood Institute: $725,875.00

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